Document Type

Article

Publication Date

11-1-2025

Abstract

South Asian and Sub-Saharan African countries, disproportionately overrepresented in the World Bank's low- and middle-income categories, bear a high burden of small and/or sick newborns. It is important to acknowledge that, in addition to reducing mortality, creating opportunities to enhance their health and well-being, thereby improving quality of life, is an essential metric for evaluating neonatal care success. With increased survival rates for small and/or sick newborns in most high-burden, resource-constrained settings, developing and strengthening specialized, structured neonatal follow-up programs to provide high-quality post-hospital care is imperative for optimizing outcomes and quality of life. This paper proposes a Systems Framework for Neonatal Follow-Up of small and/or sick newborns. While this framework applies to all settings, it is particularly pertinent in low-resource, high-burden countries, considering their unique contextual settings. This framework will provide a significant opportunity to foster meaningful engagement and partnership with a wide range of relevant local stakeholders, including families with small and/or sick newborns, as well as to identify areas for increased strategic investment. Furthermore, a multidimensional checklist aligned with the proposed framework provides a comprehensive tool for assessing neonatal follow-up readiness in health systems. The goal is to accelerate progress by transforming the delivery and accessibility of neonatal follow-up for small and/or sick newborns, thus improving the prospects for favorable long-term outcomes in this highly vulnerable population.

Keywords

global health, high-risk infant, low birth weight, neonatal follow-up, neurodevelopment, preterm birth, small vulnerable newborns

Language

English

Publication Title

Seminars in Perinatology

Rights

© 2025 The Author(s). This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/bync-nd/4.0/), which permits non-commercial copying and redistribution of the material in any medium or format, provided the original work is not changed in any way and is properly cited.

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