Document Type

Article

Publication Date

5-14-2024

Manuscript Version

vor

Abstract

Purpose of Review: This review describes advances in the diagnosis, treatment, and prevention of non-bacterial meningitis and encephalitis, with a focus on emerging viral causes of central nervous system (CNS) infection. Recent Findings: The Infectious Diseases Society of America recently published new guidelines for the management of encephalitis. Multiple articles have been published detailing emerging etiologies in human CNS infections, including analyses of neurological complications in the ongoing COVID-19 pandemic. Finally, several novel viral detection methods have been described, which may improve the detection of the specific etiologies of CNS infections (Hongyan et al. Front Neurol 14, [1]). Summary: Meningitis and encephalitis remain important causes of morbidity and mortality. They are as a whole uncommon, yet timely diagnosis, treatment, and disposition are still critical to improve patient outcomes. In clinical practice the exact cause of encephalitis is frequently unidentified, making supportive care often the only available treatment. Emergency physicians, neurologists, infectious disease doctors, and intensive care unit specialists will benefit from reviewing this discussion on emerging pathogens, as well as from reviewing advances in virology, immunology, and the imaging of inflammatory CNS conditions.

Keywords

encephalitis, meningitis, viral meningitis, aseptic meningoencephalitis, emerging viral infections

Publication Title

Current Emergency and Hospital Medicine Reports

Rights

© The Author(s) 2024. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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