Measurement of Signaling in Hematopoietic Stem Cells

Authors

Nataliya Pyatka, Case Western Reserve University
James W. Jacobberger, Case Western Reserve University

Document Type

Poster

Publication Date

4-18-2008

Abstract

The long term project will measurephosphorylated signaling molecules in hematopoieticstem cells and committed progenitorsin normal and acute myeloid leukemia(AML) samples. It will involve the evaluationof the phosphorylation state of the intracellular signaling molecules, ERK and the ribosomalprotein S6, in bone marrow cells from donors.In this short term project, the chronic myelogenousleukemia (CML) cell line, K562 (a type ofHematopoietic Stem Cells (Fig. 1)), was used in place of bone marrow cells to develop analyticalmethod.

Keywords

biochemistry, beta-lactamase

Publication Title

Intersections Source Symposium 2008

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License

Recommended Citation

Pyatka, N., & Jacobberger, J. W. (2008). Measurement of Signaling in Hematopoietic Stem Cells. Intersections Source Symposium 2008.