Author ORCID Identifier
Document Type
Article
Publication Date
11-28-2023
Abstract
The study set out to perform a systematic literature review of evidence-based interventions that target the reduction of secondary stroke risk in Africa. The review analyzed longitudinal intervention studies conducted in Sub-Saharan Africa, focusing on adult participants who had suffered a prior stroke. It encompassed publications and peer-reviewed papers sourced from reputable databases, including PubMed, Ovid, Cochrane, and Web of Science. Three randomized clinical trial (RCT) studies were included with sample sizes ranging from 16 to 400 participants, mean age ranged between 50 and 66 years, with 64.5% male participants. All studies applied multidisciplinary team interventions of enhanced patient follow-up involving care givers, nurse educators, physicians, and social workers. Interventions ranged from comprehensive patient education, tracking of medication adherence and enforcing healthy lifestyle behaviors (regular exercise, regular BP checks, and dietary changes). We found a decrease in Systolic Blood Pressure over time in 2 of 3 treatment groups, an improvement in medical adherence in all treatment groups, and a decrease in cholesterol levels in 1 treatment group. Evidence-based interventions involving multidisciplinary teams and comprehensive patient education were found to demonstrate promising results in reducing secondary stroke risk in Africa, leading to significant improvements in medical adherence and reductions in systolic blood pressure in the majority of treatment groups. However, more research is required to confirm the influence of these interventions on cholesterol levels and to establish their lasting advantages in preventing strokes among African communities.
Keywords
risk interventions, secondary stroke risk, sub-Saharan Africa
Language
English
Publication Title
Neuropsychiatric Disease and Treatment
Grant
R01NS118544
Rights
© The Author(s)2023. This is an open access article under the CC BY-NC license (https://creativecommons.org/licenses/by-nc/3.0/), which permits non-commercial reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Recommended Citation
Kaddumukasa, M., Edwards, A. M., Najjuma, J. N., Mbalinda, S. N., Nakibuuka, J., Burant, C. J., … Kaddumukasa, M. (2023). Evidence-Supported Interventions for Reducing Secondary Stroke Risk in Sub-Saharan Africa: A Systematic Review. Neuropsychiatric Disease and Treatment, 19, 2597–2606. https://doi.org/10.2147/NDT.S428627
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Psychiatric and Mental Health Commons, Psychiatry Commons, Psychiatry and Psychology Commons
Manuscript Version
Final Publisher Version