Document Type
Article
Publication Date
2-4-2025
Abstract
Obstructive sleep apnea (OSA) poses unique challenges to the perioperative management of endoscopic skull base surgery (ESBS). Currently, no consensus or guidelines exist on the reintroduction of positive airway pressure (PAP) in these patients. To better clarify the safety of PAP reintroduction after ESBS, the databases Pubmed and Embase were searched in May 2024 for studies on PAP reintroduction after ESBS. Two articles, comprising 15 patients, met the inclusion criteria. All patients resumed PAP the first night after surgery. All patients underwent ESBS for transsphenoidal pituitary resection. Only one patient experienced cerebrospinal fluid leak, and no other complications were reported. While these results suggest that early reintroduction of PAP for ESBS patients with OSA may be safer than theoretically expected, the current literature on the topic remains scarce and more research is needed.
Keywords
cerebrospinal fluid leak, pituitary adenoma, pituitary gland, pneumocephalus, positive pressure ventilation, sphenoid sinus
Language
English
Publication Title
Journal of Sleep Research
Rights
© 2025 The Author(s). This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/BY-NC-ND/4.0/), which permits non-commercial copying and redistribution of the material in any medium or format, provided the original work is not changed in any way and is properly cited.
Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Recommended Citation
Rosen, R., Rajan, J., Richter, J. Jr., Karasik, D., Cabrera, C. I., Stuyt, J. G., Rodriguez, K., D'Anza, B., Curado, T. F., & Rangarajan, S. V. (2025). Should positive airway pressure be continued uninterrupted after endoscopic skull base surgery? A review of current literature. Journal of Sleep Research, e14474. https://doi.org/10.1111/jsr.14474
Manuscript Version
Final Publisher Version