Document Type

Article

Publication Date

4-15-2014

Abstract

The future of the Alzheimer's disease (AD) field involves a more complete understanding not only the state of current scientific approaches, but also the linguistic and cultural context of preclinical and clinical research and policy activities. The challenges surrounding dementia are large and growing but are only part of broader social and health concerns. In this latter context, the current state of research in the AD area is reviewed together with necessary priorities in moving forward. Creating a more optimistic future will depend less on genetic and reductionist approaches and more on environmental and intergenerative approaches that will aid in recalibrating the study of AD from an almost exclusive focus on biochemical, molecular and genetic aspects to better encompass "real world" ecological and psychosocial models of health.

Keywords

Alzheimer's disease, amyloid, dementia, psychosocial

Language

English

Publication Title

Biochemical Pharmacology

Grant

R01AG017511

Rights

© 2013 Elsevier Inc.This peer reviewed Accepted Manuscript version is published under a Creative Commons CC-BY-NC-ND licence (https://creativecommons.org/licenses/BY-NC-ND/4.0/), which permits non-commercial copying and redistribution of the material in any medium or format, provided the original work is not changed in any way and is properly cited.

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Manuscript Version

Accepted Manuscript

 

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