Document Type
Letter to the Editor
Publication Date
2-28-2024
Abstract
To the Editor: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) represent a spectrum of severe mucocutaneous reactions characterized by extensive epidermal detachment, most commonly due to medications.1 Some viruses, such as the human immunodeficiency virus, have been found to be an independent risk factor for the development of SJS and TEN, though the mechanism is not completely understood.2 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus identified in late 2019, is most commonly associated with mild respiratory illness. However, cutaneous manifestations, including SJS and TEN, have been increasingly reported during and after COVID-19 infection.3 Therefore, the objective of this study is to determine the impact of COVID-19 infection on the incidence of SJS/TEN and to characterize mortality in patients with both SJS/TEN and COVID-19.
Keywords
COVID-19, SARS-CoV-2, Stevens-Johnson syndrome, toxic epidermal necrolysis
Publication Title
Journal of the American Academy of Dermatology
Rights
© 2024 by the American Academy of Dermatology, Inc. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/BY-NC-ND/4.0/), which permits non-commercial reuse, distribution, and reproduction in any medium, provided the original work is not changed in any way and is properly cited.
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Recommended Citation
Curtis, K. K., Dillan, M. M., Sharma, T. R., & Piktel, J. (2024). COVID-19 infection increases the development of Stevens-Johnson syndrome and toxic epidermal necrolysis: a retrospective cohort analysis. Journal of the American Academy of Dermatology, 90(6), 1300-1302.