Nutrition Faculty, Staff, Student Scholarship

 

This collection holds the creative and scholarly works of the Department of Nutrition's faculty, staff, and students. It includes scholarly content such as journal articles, book chapters, conference papers, etc.

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Submissions from 2023

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Inhibition of Wnt/β‐Catenin Pathway Overcomes Therapeutic Resistance to Abiraterone in Castration‐Resistant Prostate Cancer, Ibrahim M. Atawia, Prem P. Kushwaha, Shiv Verma, Spencer Lin, Eswar Shankar, and Sanjay Gupta

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Small Molecule Inhibitors of 15-PGDH Exploit a Physiologic Induced-Fit Closing System, Wei Huang, Hongyun Li, Janna G. Kiselar, Stephen P. Fink, Sagar Regmi, Alexander Day, Yiyuan Yuan, Mark R. Chance, Sanford D. Markowitz, and Derek J. Taylor

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Preliminary Content and Construct Validity of a New Model to Differentiate Research Skills from Evidence‐Based Practice Skills: Core, Evidence Application, Research (CEAR) Model, Raeanne Jordan, Rosanna P. Watowicz, Catherine Phillips, Rita Obeid, and Rosa K. Hand

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Prediction of Kinase-Substrate Associations Using The Functional Landscape of Kinases and Phosphorylation Sites, Serhan Yilmaz, Filipa Blasco Tavares Pereira Lopes, Mark R. Chance, and Mehmet Koyutürk

Submissions from 2022

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Temporal and Sex-Linked Protein Expression Dynamics in a Familial Model of Alzheimer's Disease, Filipa Blasco Tavares Pereira Lopes, Daniela M. Schlatzer, Rihua Wang, Xiaolin Li, Emily Feng, Mehmet Koyutürk, Xin Qi, and Mark R. Chance

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Optimizing Biomedical Discoveries as an Engine of Culture Change in an Academic Medical Center, Anne K. DeChant, Stephen Fening, Michael Haag, William Harte, and Mark R. Chance

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Survey Tools for Measuring Research or Evidence‐Based Practice Constructs in Dietetics: A Narrative Review, Rosa K. Hand

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Obesity Accelerates Acute Promyelocytic Leukemia in Mice and Reduces Sex Differences in Latency and Penetrance, John W. R. Kincaid, Gretchen Weiss, Anne E. Hill-Baskin, Heidi M. Schmidt, Ovwoioise Omoijuanfo, Cheryl L. Thompson, Rose C. Beck, and Nathan A. Berger

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Training the Next Generation of Translational Scientists: The Case Western Reserve University Translational Fellows Program, Cheryl L. Thompson, Tessianna A. Misko, and Mark R. Chance

Submissions from 2021

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Structurally Distinct External Solvent-Exposed Domains Drive Replication of Major Human Prions, Mohammad Khursheed Siddiqi, Chae Kim, Tracy Haldiman, Miroslava Kacirova, Benlian Wang, Jen Bohon, Mark R. Chance, Janna G. Kiselar, and Jiri G. Safar

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Robust Inference of Kinase Activity Using Functional Networks, Serhan Yılmaz, Daniela M. Schlatzer, Mark R. Chance, and Mehmet Koyutürk

Submissions from 2020

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Protein Footprinting: Auxiliary Engine to Power the Structural Biology Revolution, Mark R. Chance, Erik R. Farquhar, Sichun Yang, David T. Lodowski, and Janna G. Kiselar

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Discovery of a Redox Thiol Switch: Implications for Cellular Energy Metabolism, Xing-Huang Gao, Jing Wu, Ilya Bederman, Zhaofeng Gao, Dawid Krokowski, Steven M. Chirieleison, Derek Abbott, Benlian Wang, Mark Cameron, Mark R. Chance, Belinda Willard, and Maria Hatzoglou

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Inflammatory Pathway Analytes Predicting Rapid Cognitive Decline in MCI stage of Alzheimer’s disease, Jagan A. Pillai, Gurkan Bebek, Lynn M. Bekris, Aaron Bonner-Jackson, Stephen M. Rao, Mark R. Chance, and James B. Leverenz

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Proteins Inform Survival-Based Differences in Patients with Glioblastoma, L. C. Stetson, Daniela M. Schlatzer, Peter Liao, Karen Devine, Kristin Waite, Marta E. Couce, Andrew E. Sloan, Mark R. Chance, and Jill S. Barnholtz-Sloan

Submissions from 2019

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The XFP (17-BM) Beamline for X-ray Footprinting at NSLS-II, Awuri Asuru, Erik R. Farquhar, Michael Sullivan, Donald Abel, John Toomey, Mark R. Chance, and Jen Bohon

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CoPhosK: A Method for Comprehensive Kinase Substrate Annotation Using Co-Phosphorylation Analysis, Marzieh Ayati, Danica D. Wiredja, Daniela M. Schlatzer, Sean Maxwell, Ming Li, Mehmet Koyutürk, and Mark R. Chance

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Key Inflammatory Pathway Activations in the MCI Stage of Alzheimer’s disease, Jagan A. Pillai, Sean Maxwell, Lynn M. Bekris, Stephen M. Rao, Mark R. Chance, and James B. Leverenz

Submissions from 2018

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Multidomain Architecture of Estrogen Receptor Reveals Interfacial Cross-Talk Between Its DNA-Binding and Ligand-Binding Domains, Wei Huang, Yi Peng, Janna G. Kiselar, Xuan Zhao, Aljawharah Albaqami, Daniel Mendez, Yinghua Chen, Hung-Ying Kao, Mark R. Chance, and Sichun Yang

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Global Phosphoproteomics of CCR5-Tropic HIV-1 Signaling Reveals Reprogramming of Cellular Protein Production Pathways and Identifies P70-S6K1 and MK2 as HIV-Responsive Kinases Required for Optimal Infection of CD4+ T Cells, Danica D. Wiredja, Caroline O. Tabler, Daniela M. Schlatzer, Ming Li, Mark R. Chance, and John C. Tilton

Submissions from 2017

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Proteomics and Network Analyses Reveal Inhibition of Akt-mTOR Signaling in CD4+ T Cells by Mycobacterium tuberculosis Mannose-Capped Lipoarabinomannan, Ahmad F. Karim, Obondo J. Sande, Sara E. Tomechko, Xuedong Ding, Ming Li, Sean Maxwell, Clifford V. Harding, Roxana E. Rojas, Mark R. Chance, and W. Henry Boom

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Protein Footprinting Comes of Age: Mass Spectrometry for Biophysical Structure Assessment, Liwen Wang and Mark R. Chance

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Structural Basis of Ligand Interaction with Atypical Chemokine Receptor 3, Liwen Wang, Sichun Yang, and Mark R. Chance

Submissions from 2016

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Proteome and Protein Network Analyses of Memory T Cells Find Altered Translation and Cell Stress Signaling in Treated Human Immunodeficiency Virus Patients Exhibiting Poor CD4 Recovery, Sausan Azzam, Daniela M. Schlatzer, Sean Maxwell, Xiaolin Li, Douglas Bazdar, Yanwen Chen, Robert Asaad, Jill S. Barnholtz-Sloan, Mark R. Chance, and Scott F. Sieg

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A Dynamical Systems Model of Progesterone Receptor Interactions with Inflammation in Human Parturition, Douglas Brubaker, Mark R. Chance, and Sam Mesiano

Submissions from 2015

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MOBAS: Identification of Disease-Associated Protein Subnetworks Using Modularity-Based Scoring, Marzieh Ayati, Sinan Erten, Mark R. Chance, and Mehmet Koyutürk

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Apigenin Blocks IKKα Activation and Suppresses Prostate Cancer Progression, Sanjeev Shukla, Rajnee Kanwal, Eswar Shankar, Manish Datt, Mark R. Chance, Pingfu Fu, Gregory T. MacLennan, and Sanjay Gupta

Submissions from 2012

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Gene, Pathway and Network Frameworks to Identify Epistatic Interactions of Single Nucleotide Polymorphisms Derived from GWAS Data, Yu Liu, Sean Maxwell, Tao Feng, Xiaofeng Zhu, Robert C. Elston, Mehmet Koyutürk, and Mark R. Chance

Submissions from 2011

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Frontiers of Oncology: Biobanking Resources for the 21st Century, Jill Barnholtz-Sloan and Mark R. Chance

Submissions from 2010

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An Integrative -omics Approach to Identify Functional Sub-Networks in Human Colorectal Cancer, Rod K. Nibbe, Mehmet Koyutürk, and Mark R. Chance

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Prediction and testing of biological networks underlying intestinal cancer, Vishal N. Patel, Gurkan Bebek, and Mark R. Chance

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Structural Characterization of HIV gp41 with the Membrane-proximal External Region, Wuxian Shi, Jen Bohon, and Mark R. Chance

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Molecular Targets for Diabetes Mellitus-associated Erectile Dysfunction, Elizabeth Yohannes, Jinsook Chang, and Mark R. Chance

Submissions from 2009

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Discovery and Scoring of Protein Interaction Subnetworks Discriminative of Late Stage Human Colon Cancer, Rod K. Nibbe, Sanford Markowitz, Lois Myeroff, Rob M. Ewing, and Mark R. Chance

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Urinary Protein Profiles in a Rat Model for Diabetic Complications, Daniela M. Schlatzer, Jean-Eudes Dazard, Rob M. Ewing, Serguei Ilchenko, and Mark R. Chance

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Target Selection and Annotation for the Structural Genomics of the Amidohydrolase and Enolase Superfamilies, Xiaojing Zheng and Mark R. Chance

Submissions from 2008

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Proteomics Analysis Identifies Molecular Targets Related to Diabetes Mellitus-associated Bladder Dysfunction, Elizabeth Yohannes, Jinsook Chang, and Mark R. Chance

Submissions from 2005

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Structural Allostery and Binding of the Transferrin·Receptor Complex, Guozhong Xu and Mark R. Chance

Submissions from 2003

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Structural Analysis of Gelsolin Using Synchrotron Protein Footprinting, Janna G. Kiselar and Mark R. Chance