Nutrition Faculty, Staff, Student Scholarship
This collection holds the creative and scholarly works of the Department of Nutrition's faculty, staff, and students. It includes scholarly content such as journal articles, book chapters, conference papers, etc.
Submissions from 2024
Expanding Time Covered for Medical Nutrition Therapy: A Need for Clear Reporting on the Intensity of Nutrition Interventions, Rosa K. Hand
Meaningful Research in a Non-Thesis Master's Program: Description of nutritionDay in a Combined MS/DI Program, Rosa K. Hand
US Neonatal Intensive Care Unit Registered Dietitian Nutritionists Salary Description and Correlates: Results of a Survey, Rosa K. Hand and Sharon Groh-Wargo
School Nutrition Stakeholders Find Utility in MealSim: An Agent-Based Model, Melissa Pflugh Prescott
Submissions from 2023
Inhibition of Wnt/β‐Catenin Pathway Overcomes Therapeutic Resistance to Abiraterone in Castration‐Resistant Prostate Cancer, Ibrahim M. Atawia, Prem P. Kushwaha, Shiv Verma, Spencer Lin, Eswar Shankar, and Sanjay Gupta
A Haptoglobin (HP) Structural Variant Alters the Effect of APOE Alleles on Alzheimer's Disease, Haimeng Bai, Penelope Benchek, Asha R. Kallianpur, Jonathan L. Haines, and William S. Bush
Small Molecule Inhibitors of 15-PGDH Exploit a Physiologic Induced-Fit Closing System, Wei Huang, Hongyun Li, Janna G. Kiselar, Stephen P. Fink, Sagar Regmi, Alexander Day, Yiyuan Yuan, Mark R. Chance, Sanford D. Markowitz, and Derek J. Taylor
Preliminary Content and Construct Validity of a New Model to Differentiate Research Skills from Evidence‐Based Practice Skills: Core, Evidence Application, Research (CEAR) Model, Raeanne Jordan, Rosanna P. Watowicz, Catherine Phillips, Rita Obeid, and Rosa K. Hand
Prediction of Kinase-Substrate Associations Using The Functional Landscape of Kinases and Phosphorylation Sites, Serhan Yilmaz, Filipa Blasco Tavares Pereira Lopes, Mark R. Chance, and Mehmet Koyutürk
Submissions from 2022
Temporal and Sex-Linked Protein Expression Dynamics in a Familial Model of Alzheimer's Disease, Filipa Blasco Tavares Pereira Lopes, Daniela M. Schlatzer, Rihua Wang, Xiaolin Li, Emily Feng, Mehmet Koyutürk, Xin Qi, and Mark R. Chance
Optimizing Biomedical Discoveries as an Engine of Culture Change in an Academic Medical Center, Anne K. DeChant, Stephen Fening, Michael Haag, William Harte, and Mark R. Chance
Survey Tools for Measuring Research or Evidence‐Based Practice Constructs in Dietetics: A Narrative Review, Rosa K. Hand
Obesity Accelerates Acute Promyelocytic Leukemia in Mice and Reduces Sex Differences in Latency and Penetrance, John W. R. Kincaid, Gretchen Weiss, Anne E. Hill-Baskin, Heidi M. Schmidt, Ovwoioise Omoijuanfo, Cheryl L. Thompson, Rose C. Beck, and Nathan A. Berger
Training the Next Generation of Translational Scientists: The Case Western Reserve University Translational Fellows Program, Cheryl L. Thompson, Tessianna A. Misko, and Mark R. Chance
Submissions from 2021
Structurally Distinct External Solvent-Exposed Domains Drive Replication of Major Human Prions, Mohammad Khursheed Siddiqi, Chae Kim, Tracy Haldiman, Miroslava Kacirova, Benlian Wang, Jen Bohon, Mark R. Chance, Janna G. Kiselar, and Jiri G. Safar
Robust Inference of Kinase Activity Using Functional Networks, Serhan Yılmaz, Daniela M. Schlatzer, Mark R. Chance, and Mehmet Koyutürk
Submissions from 2020
Protein Footprinting: Auxiliary Engine to Power the Structural Biology Revolution, Mark R. Chance, Erik R. Farquhar, Sichun Yang, David T. Lodowski, and Janna G. Kiselar
Discovery of a Redox Thiol Switch: Implications for Cellular Energy Metabolism, Xing-Huang Gao, Jing Wu, Ilya Bederman, Zhaofeng Gao, Dawid Krokowski, Steven M. Chirieleison, Derek Abbott, Benlian Wang, Mark Cameron, Mark R. Chance, Belinda Willard, and Maria Hatzoglou
Inflammatory Pathway Analytes Predicting Rapid Cognitive Decline in MCI stage of Alzheimer’s disease, Jagan A. Pillai, Gurkan Bebek, Lynn M. Bekris, Aaron Bonner-Jackson, Stephen M. Rao, Mark R. Chance, and James B. Leverenz
Proteins Inform Survival-Based Differences in Patients with Glioblastoma, L. C. Stetson, Daniela M. Schlatzer, Peter Liao, Karen Devine, Kristin Waite, Marta E. Couce, Andrew E. Sloan, Mark R. Chance, and Jill S. Barnholtz-Sloan
Submissions from 2019
The XFP (17-BM) Beamline for X-ray Footprinting at NSLS-II, Awuri Asuru, Erik R. Farquhar, Michael Sullivan, Donald Abel, John Toomey, Mark R. Chance, and Jen Bohon
CoPhosK: A Method for Comprehensive Kinase Substrate Annotation Using Co-Phosphorylation Analysis, Marzieh Ayati, Danica D. Wiredja, Daniela M. Schlatzer, Sean Maxwell, Ming Li, Mehmet Koyutürk, and Mark R. Chance
Key Inflammatory Pathway Activations in the MCI Stage of Alzheimer’s disease, Jagan A. Pillai, Sean Maxwell, Lynn M. Bekris, Stephen M. Rao, Mark R. Chance, and James B. Leverenz
Myometrial Transcriptional Signatures of Human Parturition, Zachary Stanfield, Mark R. Chance, Sam Mesiano, and Mehmet Koyutürk
Submissions from 2018
Multidomain Architecture of Estrogen Receptor Reveals Interfacial Cross-Talk Between Its DNA-Binding and Ligand-Binding Domains, Wei Huang, Yi Peng, Janna G. Kiselar, Xuan Zhao, Aljawharah Albaqami, Daniel Mendez, Yinghua Chen, Hung-Ying Kao, Mark R. Chance, and Sichun Yang
Global Phosphoproteomics of CCR5-Tropic HIV-1 Signaling Reveals Reprogramming of Cellular Protein Production Pathways and Identifies P70-S6K1 and MK2 as HIV-Responsive Kinases Required for Optimal Infection of CD4+ T Cells, Danica D. Wiredja, Caroline O. Tabler, Daniela M. Schlatzer, Ming Li, Mark R. Chance, and John C. Tilton
Submissions from 2017
Proteomics and Network Analyses Reveal Inhibition of Akt-mTOR Signaling in CD4+ T Cells by Mycobacterium tuberculosis Mannose-Capped Lipoarabinomannan, Ahmad F. Karim, Obondo J. Sande, Sara E. Tomechko, Xuedong Ding, Ming Li, Sean Maxwell, Clifford V. Harding, Roxana E. Rojas, Mark R. Chance, and W. Henry Boom
Protein Footprinting Comes of Age: Mass Spectrometry for Biophysical Structure Assessment, Liwen Wang and Mark R. Chance
Structural Basis of Ligand Interaction with Atypical Chemokine Receptor 3, Liwen Wang, Sichun Yang, and Mark R. Chance
Submissions from 2016
Proteome and Protein Network Analyses of Memory T Cells Find Altered Translation and Cell Stress Signaling in Treated Human Immunodeficiency Virus Patients Exhibiting Poor CD4 Recovery, Sausan Azzam, Daniela M. Schlatzer, Sean Maxwell, Xiaolin Li, Douglas Bazdar, Yanwen Chen, Robert Asaad, Jill S. Barnholtz-Sloan, Mark R. Chance, and Scott F. Sieg
A Dynamical Systems Model of Progesterone Receptor Interactions with Inflammation in Human Parturition, Douglas Brubaker, Mark R. Chance, and Sam Mesiano
Submissions from 2015
MOBAS: Identification of Disease-Associated Protein Subnetworks Using Modularity-Based Scoring, Marzieh Ayati, Sinan Erten, Mark R. Chance, and Mehmet Koyutürk
Quantitative Protein Topography Analysis and High-Resolution Structure Prediction Using Hydroxyl Radical Labeling and Tandem-Ion Mass Spectrometry (MS), Parminder Kaur, Janna Kiselar, Sichun Yang, and Mark R. Chance
Proteomics of Skin Proteins in Psoriasis: From Discovery and Verification in a Mouse Model to Confirmation in Humans, Kathleen C. Lundberg, Yi Fritz, Daniela Schlatzer, Giridharan Gokulrangan, Thomas S. McCormick, Mark R. Chance, and Nicole L. Ward
Apigenin Blocks IKKα Activation and Suppresses Prostate Cancer Progression, Sanjeev Shukla, Rajnee Kanwal, Eswar Shankar, Manish Datt, Mark R. Chance, Pingfu Fu, Gregory T. MacLennan, and Sanjay Gupta
Tissue Specific Dysregulated Protein Subnetworks in Type 2 Diabetic Bladder Urothelium and Detrusor Muscle, Sara E. Tomechko, Guiming Liu, Mingfang Tao, Daniela Schlatzer, C. Thomas Powell, Sanjay Gupta, Mark R. Chance, and Firouz Daneshgari
Submissions from 2014
Crystal Structure of Clostridium Acetobutylicum Aspartate Kinase (CaAk): An Important Allosteric Enzyme for Amino Acids Production, Mark R. Chance
Multiple Glycosaminoglycan-binding Epitopes of Monocyte Chemoattractant Protein-3/CCL7 Enable it to Function as a Non-oligomerizing Chemokine, Janna G. Kiselar, Sayan Gupta, and Mark R. Chance
Integrating Phosphoproteomics in Systems Biology, Yu Liu and Mark R. Chance
Submissions from 2013
Structural Basis for the Oligomerization-State Switch from a Dimer to a Trimer of an Engineered Cortexillin-1 Coiled-Coil Variant, Saša Bjelić and Mark R. Chance
Phosphorylation of CDK9 at Ser175 Enhances HIV Transcription and is a Marker of Activated P-TEFb in CD4+ T Lymphocytes, Uri R. Mbonye, Giridharan Gokulrangan, Manish Datt, Curtis Dobrowolski, Maxwell Cooper, Mark R. Chance, and Jonathan Karn
Network Signatures of Survival in Glioblastoma Multiforme, Vishal N. Patel, Giridharan Gokulrangan, Yanwen Chen, Mehmet Koyutürk, Jill Barnholtz-Sloan, and Mark R. Chance
A Hybrid Structural Approach to Analyze Ligand Binding by the Serotonin Type 4 Receptor (5-HT4), Liwen Wang, Sayan Gupta, Tivadar Orban, Krzysztof Palczewski, and Mark R. Chance
Submissions from 2012
Insights into Substrate Specificity and Metal Activation of Mammalian Tetrahedral Aspartyl Aminopeptidase, Yuanyuan Chen, Erik R. Farquhar, Mark R. Chance, Krzysztof Palczewski, and Philip D. Kiser
Pairwise Protein Expression Classifier for Candidate Biomarker Discovery for Early Detection of Human Disease Prognosis, Parminder Kaur, Daniela Schlatzer, Kenneth Cooke, and Mark R. Chance
MAGNET: MicroArray Gene Expression and Network Evaluation Toolkit, George C. Linderman, Mark R. Chance, and Gurkan Bebek
Gene, Pathway and Network Frameworks to Identify Epistatic Interactions of Single Nucleotide Polymorphisms Derived from GWAS Data, Yu Liu, Sean Maxwell, Tao Feng, Xiaofeng Zhu, Robert C. Elston, Mehmet Koyutürk, and Mark R. Chance
Novel Urinary Protein Biomarkers Predicting the Development of Microalbuminuria and Renal Function Decline in Type 1 Diabetes, Daniela Schlatzer, Mark R. Chance, Jean-Eudes Dazard, Xiaolin Li, and Fred Hazlett
Human Biomarker Discovery and Predictive Models for Disease Progression for Idiopathic Pneumonia Syndrome Following Allogeneic Stem Cell Transplantation, Daniela M. Schlatzer, Jean-Eudes Dazard, Rob M. Ewing, Serguei Ilchenko, Saada Eid, Mark R. Chance, and Kenneth R. Cooke
Submissions from 2011
Frontiers of Oncology: Biobanking Resources for the 21st Century, Jill Barnholtz-Sloan and Mark R. Chance
Structural Analysis of Proinsulin Hexamer Assembly by Hydroxyl Radical Footprinting and Computational Modeling, Janna G. Kiselar, Manish Datt, Mark R. Chance, and Michael A. Weiss
Proteomic Signatures of Human Oral Epithelial Cells in HIV-Infected Subjects, Elizabeth Yohannes, Santosh K. Ghosh, Bin Jiang, Thomas S. McCormick, Aaron Weinberg, Edward Hill, Faddy Faddoul, and Mark R. Chance
Submissions from 2010
PETALS: Proteomic Evaluation and Topological Analysis of a Mutated Locus' Signaling, Gurkan Bebek, Vishal Patel, and Mark R. Chance
An Integrative -omics Approach to Identify Functional Sub-Networks in Human Colorectal Cancer, Rod K. Nibbe, Mehmet Koyutürk, and Mark R. Chance
Prediction and testing of biological networks underlying intestinal cancer, Vishal N. Patel, Gurkan Bebek, and Mark R. Chance
Structural Characterization of HIV gp41 with the Membrane-proximal External Region, Wuxian Shi, Jen Bohon, and Mark R. Chance
Molecular Targets for Diabetes Mellitus-associated Erectile Dysfunction, Elizabeth Yohannes, Jinsook Chang, and Mark R. Chance
Submissions from 2009
Discovery and Scoring of Protein Interaction Subnetworks Discriminative of Late Stage Human Colon Cancer, Rod K. Nibbe, Sanford Markowitz, Lois Myeroff, Rob M. Ewing, and Mark R. Chance
Urinary Protein Profiles in a Rat Model for Diabetic Complications, Daniela M. Schlatzer, Jean-Eudes Dazard, Rob M. Ewing, Serguei Ilchenko, and Mark R. Chance
Target Selection and Annotation for the Structural Genomics of the Amidohydrolase and Enolase Superfamilies, Xiaojing Zheng and Mark R. Chance
Submissions from 2008
Proteomics Analysis Identifies Molecular Targets Related to Diabetes Mellitus-associated Bladder Dysfunction, Elizabeth Yohannes, Jinsook Chang, and Mark R. Chance
Submissions from 2005
Structural Allostery and Binding of the Transferrin·Receptor Complex, Guozhong Xu and Mark R. Chance
Submissions from 2004
DNA Binding Provides a Molecular Strap Activating the Adenovirus Proteinase, Mark R. Chance
Submissions from 2003
Structural Analysis of Gelsolin Using Synchrotron Protein Footprinting, Janna G. Kiselar and Mark R. Chance
Submissions from 1995
Purification of a Variant-specific Surface Protein of Giardia lamblia and Characterization of its Metal-binding Properties, Mark R. Chance
Submissions from 1993
Temperature Dependent Coordination Effects in Base-Off Adenosyl and Methylcobalamin by X-Ray Edge Spectroscopy, Mark R. Chance
Submissions from 1992
Formation of a Square-Planar Co(I) B12 Intermediate. Implications for Enzyme Catalysis, Mark R. Chance